[Vestibular compensation and aging: An example of cellular and behavioral resilience over time].

2021 
The vestibular system has a remarkable capacity of self-repair. Vestibular compensation, a model of post-lesional plasticity of the central nervous system, refers to a set of endogenous neuroplasticity mechanisms in the vestibular nuclei in response to damage to the peripheral vestibular system, and underlying functional recovery. During aging, this "homeostatic" plasticity, although still present, diminishes and is accompanied by sensorimotor and cognitive disturbances. Regardless of age, vestibular compensation can be improved by pharmacological therapy but also by rehabilitation based on strengthening other sensory modalities such as visual and proprioceptive modalities, but also cognitive and motor components. In this article, we will first discuss neurobiological mechanisms of vestibular compensation, then document the impact of aging on this adaptive plasticity.
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