Toward Development of a Whole-genome, BAC/BIBAC-based Integrated Physical/Genetic Map of the Cotton Genome Using the Upland Genetic Standard TM-1: BAG and BIBAC Library Construction, SSR Marker Development, and Physical/Genetic Map Integration

Integrative physical mapping is the centerpieceof and essential for advanced genomics research.Upland cotton(Gossypium hirsutum L.)geneticstandard line TM-1 is used as the referencegenotype to develop a whole-genome,BAC/BIBAC-based integrated physical/genetic map ofthe cotton genome.From the TM-1 line we haveconstructed two BAC libraries with HindIII and