Increased Mortality Among Patients With Acute Leukemia Admitted on Weekends Compared to Weekdays

Abstract Background The association between weekend admission and patient outcomes has been reported in several acute illnesses but is unknown in acute leukemia. Patients and Methods We used the 2002 to 2014 Nationwide Inpatient Sample to identify patients admitted with a primary diagnosis of acute leukemia. Admissions were classified as weekend or weekday admissions for comparison. Hierarchical logistic regression models were used to analyze predictors of hospital mortality. Results There was a 22.3% decline in acute leukemia admissions in 2014 compared to 2002 and a 4% decline in in-hospital mortality (19.0%-14.9%; P P P P P P  = .01) and more complications (50.6% vs. 47.8%; P Conclusion There was significantly increased mortality among weekend admissions for acute leukemia. Mortality was reduced among patients admitted to teaching hospitals.