Final Results of the Observation Study of Biotronik Congestive Heart Failure Systems (BEATLE)

Summary Severe congestive heart failure is often accompanied by interventricular conduction disturbances. In addition to optimal pharmacological therapy, numerous studies have shown the positive effect of cardiac resynchronization therapy (CRT) realized by biventricular pacing for patients with severe congestive heart failure. Patients improved in both exercise capacity and clinical symptoms. This article describes the final results of the BEATLE (Observation of Biotronik Congestive Heart Failure Systems) observation study, whose objective was to acquire initial experience with the Triplos LV pacemaker, the Tupos LV ICD, and the Corox LV coronary sinus lead family. Special emphasis was placed on the Corox LV-H lead with its optimized three-dimensional, helix-shaped fixation mechanism in the distal area of the lead. The BEATLE observation study was able to show that biventricular pacing via a coronary vein using the resynchronization systems described above can be conducted safely and successfully.