Programming with Big Data in R (pbdR) is a series of R packages and an environment for statistical computing with big data by using high-performance statistical computation. The pbdR uses the same programming language as R with S3/S4 classes and methods which is used among statisticians and data miners for developing statistical software. The significant difference between pbdR and R code is that pbdR mainly focuses on distributed memory systems, where data are distributed across several processors and analyzed in a batch mode, while communications between processors are based on MPI that is easily used in large high-performance computing (HPC) systems. R system mainly focuses on single multi-core machines for data analysis via an interactive mode such as GUI interface. Programming with Big Data in R (pbdR) is a series of R packages and an environment for statistical computing with big data by using high-performance statistical computation. The pbdR uses the same programming language as R with S3/S4 classes and methods which is used among statisticians and data miners for developing statistical software. The significant difference between pbdR and R code is that pbdR mainly focuses on distributed memory systems, where data are distributed across several processors and analyzed in a batch mode, while communications between processors are based on MPI that is easily used in large high-performance computing (HPC) systems. R system mainly focuses on single multi-core machines for data analysis via an interactive mode such as GUI interface. Two main implementations in R using MPI are Rmpi and pbdMPI of pbdR. The idea of SPMD parallelism is to let every processor do the same amount of work, but on different parts of a large data set. For example, a modern GPU is a large collection of slower co-processors that can simply apply the same computation on different parts of relatively smaller data, but the SPMD parallelism ends up with an efficient way to obtain final solutions (i.e. time to solution is shorter). It is clear that pbdR is not only suitable for small clusters, but is also more stable for analyzing big data and more scalable for supercomputers. In short, pbdR