Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria.It is marketed in France under the trade name Octoplus and in Italy as Gramplus. Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria.It is marketed in France under the trade name Octoplus and in Italy as Gramplus. It is only functional against Gram-positive bacteria. It penetrates into human lung tissue.