P2RY1

4XNV, 4XNW502818441ENSG00000169860ENSMUSG00000027765P47900P49650NM_002563NM_001282016NM_008772NP_002554NP_001268945NP_032798P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene. P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene. The product of this gene, P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. This article incorporates text from the United States National Library of Medicine, which is in the public domain.