Amdoparvovirus

Amdoparvovirus is a genus of viruses, in the family Parvoviridae, in the subfamily Parvovirinae. Mustelids (minks, ferrets, and foxes), skunk, and raccoons serve as natural hosts. There are currently four species in this genus including the type species Carnivore amdoparvovirus 1 (Aleutian mink disease virus). Diseases associated with this genus include: progressive disorder of immune system. Group: ssDNA Viruses in genus Amdoparvovirus have non-enveloped protein particles with T=1 icosahedral symmetry. They are around 18-26 nm in diameter and contain a single linear single-stranded DNA genome of around 4.8kb in length. Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediate clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus may exit the host cell by vesicular trafficking following nuclear pore export or be released following cell lysis.Mustelids, skunk, and raccoons serve as the natural host. Transmission routes are oral and respiratory.