Nicotinamidase

In enzymology, a nicotinamidase (EC 3.5.1.19) is an enzyme that catalyzes the chemical reaction In enzymology, a nicotinamidase (EC 3.5.1.19) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are nicotinamide and H2O, whereas its two products are nicotinate and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is nicotinamide amidohydrolase. Other names in common use include nicotinamide deaminase, nicotinamide amidase, and YNDase. This enzyme participates in nicotinate and nicotinamide metabolism. As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1ILW, 1IM5, and 2H0R.