Amoebicide

An amebicide (or amoebicide) is an agent used in the treatment of amoebozoa infections, called amoebiasis. Among these agents are the following, linked to the infections they are used to treat: An amebicide (or amoebicide) is an agent used in the treatment of amoebozoa infections, called amoebiasis. Among these agents are the following, linked to the infections they are used to treat: Although Naegleria is sometimes considered amoeboid, Unlike Acanthamoeba or Balamuthia it is not closely related to the Amoebozoa (it is much more closely related to Leishmania) and agents used to treat Naegleria infections are usually addressed separately. E. histolytica infections occur in both the intestine and (in people with symptoms) in tissue of the intestine and/or liver. As a result, both tissue and luminal drugs are needed to treat the infection, one for each location. Metronidazole is usually given first, followed by Paromomycin or Diloxanide. E. dispar does not require treatment, but many laboratories (even in the developed world) do not have the facilities to distinguish this from E. histolytica. Metronidazole, or a related drug such as tinidazole, secnidazole or ornidazole, is used to destroy amoebae that have invaded tissue. These are rapidly absorbed into the bloodstream and transported to the site of infection. Because they are rapidly absorbed there is almost none remaining in the intestine.