Pheneturide

Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. Conceptually, it can be formed in the body as a metabolic degradation product from ]. It is considered to be obsolete, and is now seldom used. It is marketed in Europe, including in Poland, Spain, and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide, but is less toxic in comparison, despite still being a toxic drug. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin. Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. Conceptually, it can be formed in the body as a metabolic degradation product from ]. It is considered to be obsolete, and is now seldom used. It is marketed in Europe, including in Poland, Spain, and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide, but is less toxic in comparison, despite still being a toxic drug. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.