Renal reabsorption of chloride (Cl−) is a part of renal physiology, in order not to lose too much chloride in the urine.β intercalated cells: Cl−HCO3− exchanger Body water: Intracellular fluid/Cytosol Renal reabsorption of chloride (Cl−) is a part of renal physiology, in order not to lose too much chloride in the urine.