LISREL (linear structural relations) is a proprietary statistical software package used in structural equation modeling (SEM) for manifest and latent variables. It requires a 'fairly high level of statistical sophistication'. LISREL (linear structural relations) is a proprietary statistical software package used in structural equation modeling (SEM) for manifest and latent variables. It requires a 'fairly high level of statistical sophistication'. LISREL was developed in the 1970s by Karl Jöreskog, then a scientist at Educational Testing Service in Princeton, New Jersey, and Dag Sörbom, later both professors of Uppsala University in Sweden. The most current version is LISREL 10.1. LISREL is mainly syntax-based, although recent versions have featured a graphical user interface (GUI).