Thrombopoiesis is the process of thrombocyte generation.Thromobocytes are ligations of the cytoplasm from megakaryocytes. A single megakaryocyte can give rise to thousands of thrombocytes. Thrombopoiesis is the process of thrombocyte generation.Thromobocytes are ligations of the cytoplasm from megakaryocytes. A single megakaryocyte can give rise to thousands of thrombocytes.