Galanin receptor 1

258714427ENSG00000166573ENSMUSG00000024553P47211P56479NM_001480NM_008082NP_001471NP_032108Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene. Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene. The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-trans membrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the GI/GO family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. This article incorporates text from the United States National Library of Medicine, which is in the public domain.