SALL1

629958198ENSG00000103449ENSMUSG00000031665Q9NSC2Q9ER74Q6P5E3NM_001127892NM_002968NM_021390NP_001121364NP_002959NP_067365Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene. As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Drosophila. Sal-like 1 (Drosophila), also known as SALL1, is a protein which in humans is encoded by the SALL1 gene. As the full name suggests, it is one of the human versions of the spalt (sal) gene known in Drosophila. The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase (HDAC) complex. Defects in this gene are a cause of Townes–Brocks syndrome (TBS) as well as branchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. SALL1 has been shown to interact with TERF1 and UBE2I. This article incorporates text from the United States National Library of Medicine, which is in the public domain.