RBP1

5HA1, 5HBS, 5H8T, 5H9A594719659ENSG00000114115ENSMUSG00000046402P09455Q00915NM_002899NM_001130992NM_001130993NM_001365940NM_011254NP_001124464NP_001124465NP_002890NP_001352869NP_035384Retinol binding protein 1, cellular, also known as RBP1, is a protein that in humans is encoded by the RBP1 gene.1crb: CRYSTALLOGRAPHIC STUDIES ON A FAMILY OF CELLULAR LIPOPHILIC TRANSPORT PROTEINS. REFINEMENT OF P2 MYELIN PROTEIN AND THE STRUCTURE DETERMINATION AND REFINEMENT OF CELLULAR RETINOL-BINDING PROTEIN IN COMPLEX WITH ALL-TRANS-RETINOL1jbh: Solution structure of cellular retinol binding protein type-I in the ligand-free state1kgl: Solution structure of cellular retinol binding protein type-I in complex with all-trans-retinol1mx7: Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility1mx8: Two homologous rat cellular retinol-binding proteins differ in local structure and flexibility Retinol binding protein 1, cellular, also known as RBP1, is a protein that in humans is encoded by the RBP1 gene. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. The gene harbors four exons encoding 24, 59, 33, and 16 amino acid residues, respectively. The second intervening sequence alone occupies 19 kb of the 21 kb of the gene. Cellular retinol-binding protein-1 (CRBP-1) contributes to the maintenance of the differentiative state of endometrial cells through the regulation of bioavailability of retinol. On the converse, loss of CRBP-1 is associated with development of endometrial cancer.