Artesunate/amodiaquine

Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. It is a fixed-dose combination of artesunate and amodiaquine. Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. It is taken by mouth. Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. It is a fixed-dose combination of artesunate and amodiaquine. Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. It is taken by mouth. Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough. Safety in pregnancy is not clear; however, the medication may be used if others are not possible. It is believed to be safe for use during breastfeeding. Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms. Artesunate/amodiaquine was commercially launched in 2007. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Artesunate/amodiaquine is available as a generic medication. The wholesale cost in the developing world is about US$0.85 to US$1.52 for a course of treatment. As of 2014 it is not commercially available in the United States or United Kingdom. Early clinical trials showed that a once-a-day dosage was effective. It was subsequently clinically shown to be equally effective as artemether/lumefantrine, although it is likely to be more effective in the field due to its simpler once-a-day dosage compared to artemether/lumefantrine twice-per-day dosage. Artesunate/amodiaquine was commercially launched in 2007 as an affordable treatment for malaria, devised by DNDi in partnership with Sanofi-Aventis.