Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme. This enzyme catalyses the following chemical reaction Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme. This enzyme catalyses the following chemical reaction This peptidase from trypsin family is formed by activation of proelastase II from mammalian pancreas by trypsin.