ADAM33

1R54, 1R5580332110751ENSG00000149451ENSMUSG00000027318Q9BZ11Q08AM2Q923W9NM_001282447NM_025220NM_153202NM_001163529NM_033615NP_001269376NP_079496NP_694882NP_001157001NP_291093Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.1r54: Crystal structure of the catalytic domain of human ADAM331r55: Crystal structure of the catalytic domain of human ADAM 33 Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.