Phyllomedusa is a genus of frog from family Hylidae which inhabits Central and South America. It ranges from Costa Rica southward to Argentina. It has around 30 species. Some Phyllomedusa species produce a waxy secretion that reduces the evaporative water loss of their bodies. If they begin to dry out, they move their limbs over their backs, where the secretory glands are, and spread the lipid secretion over their entire skin. Some indigenous groups from South America use the secretions of Phyllomedusa bicolor, the giant leaf frog, in shamanic hunting practices. The substance is said to intoxicate the hunters who ingest it, causing them to temporarily improve their sensorial capacities.