Neutrophil cytosolic factor 1

1GD5, 1K4U, 1KQ6, 1NG2, 1O7K, 1OV3, 1UEC, 1W70, 1WLP65336117969ENSG00000158517ENSMUSG00000015950P14598Q09014NM_000265NM_001286037NM_010876NP_000256NP_001272966NP_035006Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene.1gd5: SOLUTION STRUCTURE OF THE PX DOMAIN FROM HUMAN P47PHOX NADPH OXIDASE1k4u: Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox1kq6: p47phox PX domain1ng2: Structure of autoinhibited p47phox1o7k: HUMAN P47 PX DOMAIN COMPLEX WITH SULPHATES1ov3: Structure of the p22phox-p47phox complex1uec: Crystal structure of autoinhibited form of tandem SH3 domain of p47phox1wlp: Solution Structure Of The P22Phox-P47Phox Complex Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. Genetic variability in the NCF1 gene has been found to be related to a higher chance of getting autoimmune diseases such as Sjögren's syndrome, rheumatoid arthritis and lupus erythematosus. Neutrophil cytosolic factor 1 has been shown to interact with: