Chloralose

Harmful if inhaledChloralose (also known as α-chloralose) is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative. Chloralose (also known as α-chloralose) is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative. Chemically, it is a chlorinated acetal derivative of glucose. It is listed in Annex I of Directive 67/548/EEC with the classification Harmful (Xn) Chloralose exerts barbiturate-like actions on synaptic transmission in the brain, including potent effects at inhibitory γ-aminobutyric acid type A (GABAA) receptors. A structural isomer of chloralose, β-chloralose (also called parachloralose in older literature), is inactive as a GABAA modulator and also as a general anesthetic.