Purine nucleoside phosphorylase

1M73, 1PF7, 1PWY, 1RCT, 1RFG, 1RR6, 1RSZ, 1RT9, 1ULA, 1ULB, 1V2H, 1V3Q, 1V41, 1V45, 1YRY, 2A0W, 2A0X, 2A0Y, 2OC4, 2OC9, 2ON6, 2Q7O, 3BGS, 3D1V, 3GB9, 3GGS, 3INY, 3K8O, 3K8Q, 3PHB, 4EAR, 4EB8, 4ECE, 4GKA486018950ENSG00000198805ENSMUSG00000115338P00491P23492NM_000270NM_013632NP_000261NP_038660Purine nucleoside phosphorylase (PNP) also known as PNPase and inosine phosphorylase is an enzyme that in humans is encoded by the NP gene.1m73: Crystal structure of human PNP at 2.3A resolution1pf7: Crystal structure of human PNP complexed with Immucillin H1pwy: Crystal structure of human PNP complexed with acyclovir1rct: Crystal structure of human purine nucleoside phosphorylase complexed with inosine1rfg: Crystal structure of human purine nucleoside phosphorylase complexed with guanosine1rr6: Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and phosphate1rsz: Structure of human purine nucleoside phosphorylase in complex with DADMe-Immucillin-H and sulfate1rt9: Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and sulfate1ula: Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors1ulb: Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors1v2h: Crystal structure of human PNP complexed with guanine1v3q: Structure of human PNP complexed with DDI1v41: Crystal structure of human PNP complexed with 8-Azaguanine1v45: Crystal structure of human PNP complexed with 3-deoxyguanosine1yry: Crystal structure of human PNP complexed with MESG2a0w: Structure of human purine nucleoside phosphorylase H257G mutant2a0x: Structure of human purine nucleoside phosphorylase H257F mutant2a0y: Structure of human purine nucleoside phosphorylase H257D mutant2oc4: Crystal structure of human purine nucleoside phosphorylase mutant H257D with Imm-H2oc9: Crystal structure of human purine nucleoside phosphorylase mutant H257G with Imm-H2on6: Crystal structure of human purine nucleoside phosphorylase mutant H257F with Imm-H Purine nucleoside phosphorylase (PNP) also known as PNPase and inosine phosphorylase is an enzyme that in humans is encoded by the NP gene. In enzymology, a purine-nucleoside phosphorylase (EC 2.4.2.1) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are purine nucleoside and phosphate, whereas its two products are purine and alpha-D-ribose 1-phosphate. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is purine-nucleoside:phosphate ribosyltransferase.