NCOA6

23054n/aENSG00000198646n/aQ14686n/aNM_001242539NM_014071NM_001318240n/aNP_001229468NP_001305169NP_054790n/aNuclear receptor coactivator 6 is a protein that in humans is encoded by the NCOA6 gene. Nuclear receptor coactivator 6 is a protein that in humans is encoded by the NCOA6 gene. The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases. NCOA6 has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.