Pisodonophis semicinctus is an eel in the family Ophichthidae (worm/snake eels). It was described by John Richardson in 1848. It is a marine, subtropical eel which is known from the eastern Atlantic Ocean, including Morocco, Angola, and Algeria. It dwells at a depth range of 10 to 30 metres (33 to 98 ft), and inhabits the continental shelf, where it forms burrows in sand and mud. Males can reach a maximum total length of 80 centimetres (31 in), but more commonly reach a TL of 60 centimetres (24 in). P. semicinctus is of commercial interest to fisheries. Its diet consists of mollusks and benthic crustaceans.