FOSL1

806114283ENSG00000175592ENSMUSG00000024912P15407P48755NM_001300844NM_001300855NM_001300856NM_001300857NM_005438NM_010235NP_001287773NP_001287784NP_001287785NP_001287786NP_005429NP_034365Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene. Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene. The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. FOSL1 has been shown to interact with USF1 (human gene) and C-jun. This article incorporates text from the United States National Library of Medicine, which is in the public domain.