Stem cell factor

1EXZ, 1SCF, 2E9W425417311ENSG00000049130ENSMUSG00000019966P21583P20826NM_003994NM_000899NM_013598NM_001347156NP_000890NP_003985NP_001334085NP_038626Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis.1exz: STRUCTURE OF STEM CELL FACTOR1scf: HUMAN RECOMBINANT STEM CELL FACTOR Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. The gene encoding stem cell factor (SCF) is found on the Sl locus in mice and on chromosome 12q22-12q24 in humans. The soluble and transmembrane forms of the protein are formed by alternative splicing of the same RNA transcript,