Human coronavirus 229E

Human coronavirus 229E is a single-stranded, positive-sense, RNA virus species in the genus Alphacoronavirus of the subfamily Coronavirinae, in the family Coronaviridae, of the order Nidovirales. Along with Human coronavirus OC43, it is responsible for the common cold. Human coronavirus 229E is a single-stranded, positive-sense, RNA virus species in the genus Alphacoronavirus of the subfamily Coronavirinae, in the family Coronaviridae, of the order Nidovirales. Along with Human coronavirus OC43, it is responsible for the common cold. HCoV-229E transmits via droplet-respiration and fomites. HCoV-229E is associated with a range of respiratory symptoms, ranging from the common cold to high-morbidity outcomes such as pneumonia and bronchiolitis. It is also among the Coronaviruses most frequently codetected with other respiratory viruses, particularly with Human respiratory syncytial virus (HRSV). HCoV-229E is one of the four human coronaviruses which include HCoV-NL63, HCoV-OC43, and HCoV-HKU1 and are globally distributed. However, the four viruses are detected in different parts of the world at different times of the year.