TNIK

2X7F, 5CWZ, 5AX923043665113ENSG00000154310ENSMUSG00000027692Q9UKE5P83510NM_001161565NM_001161566NM_015028NM_001163007NM_001163008NM_001163009NM_026910NP_001155037NP_001155038NP_055843NP_001156479NP_001156480NP_001156481NP_081186TRAF2 and NCK-interacting protein kinase is an enzyme that in humans is encoded by the TNIK gene. TRAF2 and NCK-interacting protein kinase is an enzyme that in humans is encoded by the TNIK gene. Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function. TNIK has been shown to interact with KIAA0090, although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal changes.