Orexin receptor 1

4ZJ8, 4ZJC3061230777ENSG00000121764ENSMUSG00000028778O43613P58307NM_001525NM_001163027NM_198959NM_001305392NM_001357258NP_001516NP_001156499NP_001292321NP_945197NP_001344187Orexin receptor type 1 (Ox1R or OX1), also known as hypocretin receptor type 1 (HcrtR1), is a protein that in humans is encoded by the HCRTR1 gene. Orexin receptor type 1 (Ox1R or OX1), also known as hypocretin receptor type 1 (HcrtR1), is a protein that in humans is encoded by the HCRTR1 gene. The orexin 1 receptor (OX1), is a G-protein coupled receptor that is heavily expressed in projections from the lateral hypothalamus and is involved in the regulation of feeding behaviour. OX1 selectively binds the orexin-A neuropeptide. It shares 64% identity with OX2. This article incorporates text from the United States National Library of Medicine, which is in the public domain.