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RNA polymerase V

RNA polymerase V is a multisubunit plant specific RNA polymerase found in nucleus. Together withRNA polymerase IV required for normal function and biogenesis of small interfering RNA (siRNA). Pol V is involved in siRNA-directed DNA methylation pathway which leads to heterochromatic silencing. RNA polymerase V is a multisubunit plant specific RNA polymerase found in nucleus. Together withRNA polymerase IV required for normal function and biogenesis of small interfering RNA (siRNA). Pol V is involved in siRNA-directed DNA methylation pathway which leads to heterochromatic silencing. RNA polymerase V is composed of 12 subunits that are paralogous to RNA polymerase II subunits. Two largest subunits (catalytic site) is the most conserved region sharing similarity with eukaryotic and bacterial polymerases.

[ "RNA silencing", "Transposable element", "Small interfering RNA", "Heterochromatin", "DNA methylation" ]
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