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GAS6

1H30, 2C5D, 4RA0262114456ENSG00000183087ENSMUSG00000031451Q14393Q61592NM_001143946NM_000820NM_001143945NM_019521NP_000811NP_062394Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts.1h30: C-TERMINAL LG DOMAIN PAIR OF HUMAN GAS62c5d: STRUCTURE OF A MINIMAL GAS6-AXL COMPLEX Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43% amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. Gas6 is a gamma-carboxyglutamic acid (Gla) domain-containing protein thought to be involved in the stimulation of cell proliferation. Gas6 has been shown to interact with AXL receptor tyrosine kinase, MerTK and TYRO3.

[ "Receptor tyrosine kinase", "Apoptosis", "AXL Protein", "TYRO3", "Growth arrest-specific protein 6", "AXL Inhibitor BGB324", "C-Mer Tyrosine Kinase" ]
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