USF2

739222282ENSG00000105698ENSMUSG00000058239Q15853Q64705NM_003367NM_207291NM_001321150NM_011680NP_001308079NP_003358NP_997174NP_035810Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene. Upstream stimulatory factor 2 is a protein that in humans is encoded by the USF2 gene. This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through Pyridine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. USF2 has been shown to interact with USF1 (human gene), PPRC1 and BRCA1. The USF2 gene is repressed by the microRNA miR-10a.