The Ski complex is a multi-protein complex involved in the 3' end degradation of messenger RNAs in yeast. The complex consists of three main proteins, the RNA helicase Ski2 and the proteins Ski3 and Ski8. In yeast, the complex guides RNA molecules to the exosome complex for degradation via a fourth protein, called Ski7, which contains a GTPase-like protein. The Ski complex is a multi-protein complex involved in the 3' end degradation of messenger RNAs in yeast. The complex consists of three main proteins, the RNA helicase Ski2 and the proteins Ski3 and Ski8. In yeast, the complex guides RNA molecules to the exosome complex for degradation via a fourth protein, called Ski7, which contains a GTPase-like protein.