In enzymology, a linoleate isomerase (EC 5.2.1.5) is an enzyme that catalyzes the chemical reaction In enzymology, a linoleate isomerase (EC 5.2.1.5) is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate. This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is linoleate Delta12-cis-Delta11-trans-isomerase. This enzyme is also called linoleic acid isomerase. This enzyme participates in linoleic acid metabolism.