Polygodial is an active constituent of Dorrigo Pepper, Mountain Pepper, Horopito, Canelo, Paracress and Water-pepper. Furthermore, Polygodial is synthetized by Dendrodoris limbata. Polygodial is an active constituent of Dorrigo Pepper, Mountain Pepper, Horopito, Canelo, Paracress and Water-pepper. Furthermore, Polygodial is synthetized by Dendrodoris limbata. Chemically it is a drimane-type sesquiterpene dialdehyde of formula C15H22O2.