KCNJ3

1N9P, 1U4E, 2QKS, 3K6N376016519ENSG00000162989ENSMUSG00000026824P48549P63250NM_002239NM_001260508NM_001260509NM_001260510NM_008426NM_001304810NM_001355118NP_001247437NP_001247438NP_001247439NP_002230NP_001291739NP_032452NP_001342047Potassium inwardly-rectifying channel, subfamily J, member 3, also known as KCNJ3 or Kir3.1, is a human gene.1n9p: Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier Potassium Channel 11u4e: Crystal Structure of Cytoplasmic Domains of GIRK1 channel Potassium inwardly-rectifying channel, subfamily J, member 3, also known as KCNJ3 or Kir3.1, is a human gene. Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a hetero-tetrameric pore-forming complex. KCNJ3 has been shown to interact with KCNJ5. This article incorporates text from the United States National Library of Medicine, which is in the public domain.