NFATC3

2XRW, 2XS0477518021ENSG00000072736ENSMUSG00000031902Q12968P97305NM_173165NM_004555NM_173163NM_173164NM_010901NM_001368796NM_001368797NP_004546NP_775186NP_775188NP_004546.1NP_775188.1n/aNuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene. Nuclear factor of activated T-cells, cytoplasmic 3 is a protein that in humans is encoded by the NFATC3 gene. The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene. This article incorporates text from the United States National Library of Medicine, which is in the public domain.