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Embryonal carcinoma

Embryonal carcinoma is a relatively uncommon type of germ cell tumour that occurs in the ovaries and testes. Embryonal carcinoma is a relatively uncommon type of germ cell tumour that occurs in the ovaries and testes. The presenting features may be a palpable testicular mass or asymmetric testicular enlargement in some cases. The tumour may present as signs and symptoms relating to the presence of widespread metastases, without any palpable lump in the testis. The clinical features associated with metastasising embryonal carcinoma may include low back pain, dyspnoea, cough, haemoptysis, haematemesis and neurologic abnormalities. Males with embryonal carcinoma tend to have a normal range serum AFP. The finding of elevated AFP is more suggestive of a mixed germ cell tumour, with the AFP being released by a yolk sac tumour component. The gross examination usually shows a two to three centimetre pale grey, poorly defined tumour with associated haemorrhage and necrosis.

[ "Cellular differentiation", "Cell culture", "Teratocarcinoma Stem Cells", "Mediastinal Embryonal Carcinoma", "Embryonal Carcinoma Cells", "Polyembryoma", "F9 Embryonal Carcinoma Cells" ]
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