The brown tree snake (Boiga irregularis) is an arboreal rear-fanged colubrid snake native to eastern and northern coastal Australia, eastern Indonesia (Sulawesi to Papua), Papua New Guinea, and a large number of islands in northwestern Melanesia. This snake is infamous for being an invasive species responsible for extirpating the majority of the native bird population in Guam. It is also one of the very few colubrids found in Australia, where elapids are more common. The brown tree snake preys upon birds, lizards, bats, and rats and other small rodents in its native range. It preys on birds and shrews in Guam. Due to the availability of prey and lack of predators in introduced habitats such as Guam, they have been known to grow to larger sizes than their normal 1 to 2 m (3.3 to 6.6 ft) in length. The longest recorded length of this species is one found on Guam measuring 3 m (9.8 ft). The reproductive characteristics of the brown tree snake have not been widely studied. The female is known to produce four to 12 oblong eggs, 42–47 mm (1.7–1.9 in) long and 18–22 mm (0.71–0.87 in) wide with leathery shells. Females may produce up to two clutches per year depending upon seasonal variations in climate and prey abundance. The female deposits the eggs in hollow logs, rock crevices, and other sites where they are likely protected from drying and high temperatures. Populations on Guam may reproduce year round. The brown tree snake is a nocturnal, rear-fanged colubrid, possessing two small, grooved fangs at the rear of the mouth. Due to the placement of the fangs and their grooved rather than hollow architecture, the venom is difficult to convey into a bite on a human, and thus is only delivered in small doses. The venom appears to be weakly neurotoxic and possibly cytotoxic with localized effects that are trivial for adult humans; serious medical consequences have been limited to children, who are more susceptible because of their low body mass. The snake has been reported as aggressive, but is not considered dangerous to an adult human. The venom seems to be primarily used to subdue lizards, which can be more easily positioned in the rear of the mouth for venom delivery. Shortly after World War II, and before 1952, the brown tree snake was accidentally transported from its native range in the South Pacific to Guam, probably as a stowaway in ship cargo or by crawling into the landing gear of Guam-bound aircraft. As a result of abundant prey resources on Guam and the absence of natural predators apart from feral pigs and mangrove monitors, brown tree snake populations reached unprecedented numbers. Snakes caused the extirpation of most of the native forest vertebrate species; thousands of power outages affecting private, commercial, and military activities; widespread loss of domestic birds and pets; and considerable emotional trauma to residents and visitors alike when snakes invaded human habitats with the potential for envenomation of small children. Since Guam is a major transportation hub in the Pacific, numerous opportunities exist for the brown tree snakes on Guam to be introduced accidentally to other Pacific islands as passive stowaways in ship and air traffic from Guam. To minimize this threat, trained dogs are used to search, locate, and remove brown tree snakes before outbound military and commercial cargo and transportation vessels leave the island. Numerous sightings of this species have been reported on other islands including Wake Island, Tinian, Rota, Okinawa, Diego Garcia, Hawaii, and even Texas in the continental United States. Hawaii is especially at heavy risk to the snake, as direct military flights between Guam and Hawaii are allowed and brown tree snakes are regularly intercepted at landing areas. A successful introduction could pose an immense threat to the already highly-threatened endemic birds of the islands. An incipient population is probably established on Saipan. Acetaminophen has been used to help eradicate the snake on Guam. The brown tree snake is a nocturnal, arboreal species that uses visual and chemical cues in hunting in the tropical rainforest canopy and/or on the ground. It is a member of the subfamily Colubrinae, genus Boiga, which is a group of roughly twenty five species that are referred to as 'cat-eyed' snakes for their vertical pupils. The brown tree snake is generally 1-2 m (3-6 ft) in length in its native range. The snake is long and slender, which facilitates its climbing ability and allows it to pass through tiny spaces in buildings, logs, and other shaded locations, where it seeks refuge during daylight. Variations in coloration occur in the snake's native range, ranging from a lightly patterned brown to yellowish/green or even beige with red, saddle-shaped blotches. They are rear-fanged, have a large head in relation to their body, and can survive for extended periods of time without food. The brown tree snake is a generalist feeder known to eat a wide variety of foods, when threatened is highly aggressive and tends to lunge and strike the aggressor repeatedly. The snake has numerous teeth, but only the last two on each side of the upper jaw have grooves, which inject venom as it bites. Therefore, the snake’s mouth must be opened as wide as possible to insert and expose its fangs. A chewing movement is used by the snake to inject the venom by means of capillary action along the grooved fangs. The venom is used to subdue and kill prey on which the snake feeds; however, the venom is not considered dangerous to adult humans. In addition to subduing its victim with its venom, the brown tree snake often wraps its body around the prey, like a constrictor, to immobilize the prey while chewing and consuming the animal.