FBLN1

FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein.219214114ENSG00000077942ENSMUSG00000006369P23142Q08879NM_006487NM_001996NM_006485NM_006486NM_010180NM_001347088NP_001987NP_006476NP_006477NP_006478NP_001334017NP_034310Fibulin-1 is a secreted glycoprotein that is found in association with extracellular matrix structures including fibronectin-containing fibers, elastin-containing fibers and basement membranes. Fibulin-1 binds to a number of extracellular matrix constituents including fibronectin, nidogen-1, and the proteoglycan, versican. Fibulin-1 is also a blood protein capable of binding to fibrinogen.Fibulin-1 has modular domain structure and includes a series of nine epidermal growth factor-like modules followed by a fibulin-type module, a module found in all members of the fibulin gene family.FBLN1 has been shown to interact with: