NEUROD2

476118013ENSG00000171532ENSMUSG00000038255Q15784Q62414NM_006160NM_010895NP_006151NP_035025Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene. Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene. This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. NEUROD2 has been shown to interact with Protein kinase N1. This article incorporates text from the United States National Library of Medicine, which is in the public domain.