DLX2

174613392ENSG00000115844ENSMUSG00000023391Q07687P40764NM_004405NM_010054NP_004396NP_004396.1NP_034184Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.2djn: The solution structure of the homeobox domain of human Homeobox protein DLX-5 Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene. Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. DLX2 has been shown to interact with DLX5, MSX1 and Msh homeobox 2.