Cellular microarray

A cellular microarray (or cell microarray) is a laboratory tool that allows for the multiplex interrogation of living cells on the surface of a solid support. The support, sometimes called a 'chip', is spotted with varying materials, such as antibodies, proteins, or lipids, which can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in phenotype, or detection of a response from the cell, such as a specific secreted factor. A cellular microarray (or cell microarray) is a laboratory tool that allows for the multiplex interrogation of living cells on the surface of a solid support. The support, sometimes called a 'chip', is spotted with varying materials, such as antibodies, proteins, or lipids, which can interact with the cells, leading to their capture on specific spots. Combinations of different materials can be spotted in a given area, allowing not only cellular capture, when a specific interaction exists, but also the triggering of a cellular response, change in phenotype, or detection of a response from the cell, such as a specific secreted factor.