Palmitoyl-CoA hydrolase

In enzymology, a palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of long chain fatty acyl thioesters of acyl carrier protein or coenzyme A to form free fatty acid and the respective thiol. In enzymology, a palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of long chain fatty acyl thioesters of acyl carrier protein or coenzyme A to form free fatty acid and the respective thiol. p a l m i t o y l − S C o A + H 2 O ⇄ C o A S H + p a l m i t a t e {displaystyle palmitoyl-SCoA+H_{2}O ightleftarrows CoASH+palmitate} Thus, the two substrates of this enzyme are palmitoyl-CoA and H2O, whereas its two products are CoA and palmitate. It has a strict specificity for thioesters with a chain link greater than C10.