The mandibular foramen is an opening on the internal surface of the ramus of the mandible for divisions of the mandibular nerve and blood vessels to pass through.View from behind of the mandibular foramina (red). The mandibular foramen is an opening on the internal surface of the ramus of the mandible for divisions of the mandibular nerve and blood vessels to pass through. The mandibular foramen is an opening on the internal surface of the ramus of the mandible for divisions of the mandibular nerve and blood vessels to pass through.