Dog breeding is the practice of mating selected dogs with the intent to maintain or produce specific qualities and characteristics. When dogs reproduce without such human intervention, their offspring's characteristics are determined by natural selection, while 'dog breeding' refers specifically to the artificial selection of dogs, in which dogs are intentionally bred by their owners. Breeding relies on the science of genetics, so the breeder with a knowledge of canine genetics, health, and the intended use for the dogs attempts to breed suitable dogs.Few hours oldThree days oldFew weeks oldSeven weeks oldTwelve weeks old Dog breeding is the practice of mating selected dogs with the intent to maintain or produce specific qualities and characteristics. When dogs reproduce without such human intervention, their offspring's characteristics are determined by natural selection, while 'dog breeding' refers specifically to the artificial selection of dogs, in which dogs are intentionally bred by their owners. Breeding relies on the science of genetics, so the breeder with a knowledge of canine genetics, health, and the intended use for the dogs attempts to breed suitable dogs. The female parent of puppies is referred to as the dam and the male parent, is referred to as the sire. A litter is those puppies born from the same pregnancy. A whelp is a newborn puppy and giving birth in dogs is called whelping. Dogs commonly give birth in a whelping box, a simple box or pen provided to the dam to help shelter and contain the puppies. A person who intentionally mates dogs to produce puppies is referred to as a dog breeder. Line breeding is the planned breeding of dogs with their relatives. This is done to strengthen the appearance of specific desired traits in offspring. Line breeding is differentiated from inbreeding by excluding pairings between parents and offspring, and between full siblings. Outcrossing is the planned breeding between two unrelated dogs, used to increase genetic diversity in a breed and decrease genetic issues or abnormalities inherited from line breeding or inbreeding. Dogs reach puberty between 6-24 months old. Female dogs will start having an estrus (also spelled 'estrous') cycle. A dog in estrus, also known as being 'in heat', can become pregnant during this 3-21 day period. Humans have maintained populations of useful animals around their places of habitat since pre-historic times. Over these millennia, domesticated dogs have developed into distinct types, or groups, such as livestock guardian dogs, hunting dogs, and sighthounds. To maintain these distinctions, humans have intentionally mated dogs with certain characteristics to encourage those characteristics in the offspring. Through this process, hundreds of dog breeds have been developed. Artificial selection in dog breeding has influenced behavior, shape, and size of dogs. It is believed when human civilization moved towards agrarian societies, dogs were selectively bred for smaller size and more docile behavior. These traits made it more comfortable for humans and dogs to live together. It has been seen that these traits can even prompt an adult female wolf to act more defensively of dog puppies than of wolf puppies. The example of canine neoteny goes even further, in that the various dog breeds are differently neotenized according to the type of behavior that was selected. Other researchers believe that because this comparison is based on the gray wolf, which is not the ancestor of the dog, that this comparison is invalid. Further research indicates that the concept of neoteny as a means of distinguishing dogs from wolves is baseless. With the development of breed clubs and kennel clubs during the mid-19th century, dog breeding became more rigorous and many breeds were developed during this time. Dog breeding became more systemic to preserve unique mutations such as shortened legs, a shortened face, new fur colors and textures. The increased popularity of dog shows that judged a dog’s look more than its working ability led to different goals when breeding. Dogs bred for show rather than performance tended to develop more exaggerated and extreme features to meet breed standards. One example of this change in breeding goals is the pronounced sloped back in the modern German Shepherd breed, compared to the straight back of working pedigrees. The Shar Pei is an example of how differing breed standards can influence the direction breeders take a dog and which traits are exaggerated. The Western Shar Pei has been bred to have a meatier mouth and wrinklier skin than the traditional Chinese Shar Pei it originated from.