GPRC5A

9052232431ENSG00000013588ENSMUSG00000046733Q8NFJ5Q8BHL4NM_003979NM_181444NP_003970NP_852109Retinoic acid-induced protein 3 is a protein that in humans is encoded by the GPRC5A gene. Retinoic acid-induced protein 3 is a protein that in humans is encoded by the GPRC5A gene. This gene encodes a member of the type 3 G protein-coupled receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoic acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. GPRC5A is one of only a handful of genes known in the literature that are post-transcriptionally controlled by miRNAs through their 5'UTR. GPRC5A is dysregulated in many human cancers and in other diseases. This article incorporates text from the United States National Library of Medicine, which is in the public domain.