Enediyne

The enediynes are a class of cyclic molecules whose core ring contains an alkene conjugated to two alkynes. This core ring consists of a total of either nine or ten members. Other functional groups are usually attached to the nine- or ten-membered ring, providing each enediyne with additional chemical properties. The enediynes are a class of cyclic molecules whose core ring contains an alkene conjugated to two alkynes. This core ring consists of a total of either nine or ten members. Other functional groups are usually attached to the nine- or ten-membered ring, providing each enediyne with additional chemical properties. Since the discovery of calicheamicin and esperamicin in 1987, several more enediynes have been discovered as natural products in bacteria. Synthetic enediynes have also been designed to improve the functionality of the naturally occurring enediynes.